Excessive sweating is known medically as Hyperhydrosis, is caused by stimulation of the sweat glands by nerve endings which descend from higher centers in the brain. These nerves respond to emotional stresses like intimate social situations, public speaking, physical stresses, and increased body temperature that comes with exercise or hot humid weather. Most people with excessive sweating are bothered primarily when they are emotionally stressed, physically active, or over-heated. Botox® can prevent sweating for months by blocking the release of the neurotransmitter, i.e., acetylcholine, from the nerve endings, that causes the glands to produce sweat.
Fifteen to twenty drops of Botox® are injected via a very small needle into the hair-bearing skin of each underarm. Normal activity can be immediately resumed, while heavy exercise should be avoided for several hours.
Underarm sweating will be decreased by 90% within 48 hours and full effect will be seen within one week. There may be simultaneous disappearance of odor associated with decreased sweating, but this is not consistent.
Most patients will obtain the benefit of dryness with one treatment of Botox® for six to ten months.
What are the risks and complications?
Complications from injection into the axillary skin include tiny bruises which fade in a few days, and small persistent areas of sweating that may need a second treatment. There is no risk of numbness or permanent change in the axillary skin, and the risk of temporary muscle weakness is remote.